Actors Anne Hathaway and Jake Gyllenhaal are among the best in Hollywood.
A pharmaceutical salesman and a woman with Parkinson's disease who fall in love are the subjects of the movie.
Gyllenhaal and Heath Ledger had the key parts, with Anne Hathaway filling out the supporting cast. It was directed by Ang Lee.
'Love and Other Drugs' and 'Brokeback Mountain' both showed off Gyllenhaal and Hathaway's incredible on-screen chemistry.
Gyllenhaal and Hathaway have never been romantically connected in real life, despite their incredible on-screen chemistry.
'Angels in America' was a stage piece that Gyllenhaal and Hathaway also collaborated on.
The incredible on-screen connection between Jake Gyllenhaal and Anne Hathaway is a credit to both of their acting prowess.